Non-Surgical · Comparison
A collagen stimulator and a repair booster, chosen by the complaint
Apgujeong, Gangnam, Seoul | Board-certified plastic surgeon, Dr. Jonghwan Choi
Both held at the Apgujeong clinic · KHIDI-registered
The comparison
The short answer
Choose by the complaint. Juvelook is a collagen stimulator, poly-D,L-lactic acid carried with hyaluronic acid, used where skin has thinned and lost body and for texture and pores. Rejuran is a polynucleotide booster made from purified salmon DNA fragments, used where skin looks tired, dry or worn and needs repair more than bulk. Rewind holds both.
They serve different layers of the same list of complaints, and a single course can include both when the doctor judges it useful.
Patients often arrive having read that both are skin boosters, which is true and not very helpful. The category covers products with very different jobs. Juvelook leaves particles behind that the skin gradually builds collagen around, so its effect is felt as firmness and softness. Rejuran leaves no scaffold; its nucleotide chains act as a repair signal and are metabolised, so its effect shows as skin quality and has to be maintained.
The consultation question is therefore easy to state: is the skin mainly thin, or mainly worn? Many faces are both, and the answer then becomes a matter of order.
Side by side
Most decisions between these two products come down to the four points below, each of which can be checked against your own skin.
Mechanism
The two products are injected into the same layer of skin and then do quite different things there.
The polylactic acid in a Juvelook vial is broken down slowly while the surrounding tissue lays down new collagen. Research on the biological basis of polylactic-acid augmentation describes this as a tissue response to the particles, so the result arrives over weeks and the stronger vial is placed with care.
The polynucleotide chains in Rejuran carry no volume. They are placed as a grid of small deposits, act on the skin's repair behaviour and are then broken down, so what improves is quality and hydration, and the effect is kept by repeating it.
Rejuran Eye is a dedicated line for the thin skin below the eye. On the Juvelook side, the poly-D,L form has been studied for nonsurgical lower eyelid rejuvenation in Asian patients. Which one suits your lower lid depends on whether the issue is crepey texture or hollowness.
Because Rejuran is derived from salmon, any sensitivity to fish-derived material is raised before it is chosen. For Juvelook, the key history question is any previous lump or nodule after a biostimulator injection.

Sequencing
Yes, when the skin needs both jobs done. Rewind lists the two in separate packages, Rejuran Healer in its recovery programme and Juvelook Skin in its elasticity programme, which reflects the different complaints they address. A plan that uses both is written for you by the doctor.
When skin is irritated, dry or recovering, the doctor may begin with the repair booster and add the stimulator later. When thinning is the main complaint, the order can be reversed. Rewind has no published fixed sequence; it is set on your skin.
Combining products means the doctor has to judge what each one did. Appointments are spaced so the effect of one can be seen before the next is added, and the intervals are written into your plan at consultation.
If the concern is a fold or a jaw line that has dropped, neither a booster nor a stimulator will move it. The doctor says so at the first visit and explains the non-surgical options for laxity.
On the day

Fig. 04 · The entrance to the treatment floor

Fig. 05 · Injectable treatments are carried out here
You are examined by the medical director, the product and zone are agreed, and the injection follows. For Juvelook, the clinic's record specifies a numbing cream and no sutures. For Rejuran, comfort is raised at booking and settled with the doctor before the first point is placed. The clinic takes appointments only, on the fourth and fifth floors of the Richro Building in Gangnam, Seoul, closing at 19:00 on Monday, Tuesday, Wednesday and Friday and at 16:00 on Saturday.
Tell the clinic about any filler, booster or energy treatment you have had in the same area, and when. It changes both the choice between these two products and the timing of either one.
Pricing
Juvelook is listed per vial and Rejuran by volume. Because the two are dosed differently, the fair comparison is between whole plans, which the doctor writes after the examination.
All five rates are list prices with VAT charged on top at payment. Where numbing is used, it sits inside the listed rate. A course combining the two products is costed line by line from this list once the plan is set.
Suitability
Neither is recommended when the concern is descent, with active infection or inflamed acne at the site, during pregnancy or breastfeeding, or shortly after a different injection in the same zone. The doctor will also advise against starting either one a few weeks before an important date, since both build their effect over time.
Recovery
Rewind issues a separate aftercare sheet for each product. They overlap on heat, alcohol and sun, and they differ on whether the skin should be touched.
Both are injections and share the common risks: bruising, swelling, redness and tenderness. With Juvelook, firm nodules in the treated plane are the complication monitored for; with Rejuran, an allergic reaction is the specific concern. Infection and vascular occlusion are rare with either and are serious. Contact the clinic promptly about increasing pain, pale or dusky skin, or a new lump.
At Rewind, one board-certified plastic surgeon carries every case — from the first consultation to the final follow-up. Because a face is a story, and a story deserves a single author.
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Scientific evidence
These papers cover the Juvelook side of the comparison: the biological basis of polylactic-acid augmentation, a study of the poly-D,L form under the lower eyelid in Asian patients, and a case study of injectable poly-L-lactic acid for acne scarring. Published work on polynucleotide preparations is listed on the Rejuran page. None of these studies was conducted at Rewind.