Non-Surgical · Skin Booster

Rejuran

Polynucleotide injections, planned by a plastic surgeon

Gangnam, Seoul | Board-certified plastic surgeon, Dr. Jonghwan Choi
KHIDI-registered for international patients · Apgujeong Rewind

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Define

Rejuran

What is Rejuran, and what goes into the syringe?

The short answer

Rejuran is a polynucleotide skin booster. Long-chain DNA fragments, purified from salmon, are injected into the dermis as a grid of small deposits. Nothing is being filled or lifted: the material is read by the skin as a repair signal, and whatever change follows is built by your own tissue over the weeks after the session.

Rewind lists this treatment inside its skin-booster menu alongside its other injectable lines. The volume and the line — Healer for facial skin, Eye for the thin skin below the eye — are set with the doctor at consultation.

The category word matters when you compare quotes. A skin booster is a product class, and polynucleotide is one chemistry inside that class; hyaluronic-acid water injections, exosome preparations and polylactic-acid stimulators all sit in the same menu and answer different questions. Rewind separates them at diagnosis instead of selling the menu as one thing.

The practice is a plastic surgery clinic, so an injectable is never the only tool in the room. When the complaint you describe is skin quality, a booster is a reasonable place to start. When the complaint is a fold or a jaw line that has dropped, the surgeon says so at the consultation and shows you what a booster would and would not move.

Dr. Jonghwan Choi reviewing a patient's skin at the consultation desk
Fig. 01 — Consultation desk, Rewind Plastic Surgery
Map

Placement

Where on the face polynucleotide boosters are usually placed

Published work on long-chain polynucleotide injection describes facial skin rejuvenation as the main application, with the periocular area treated as a separate problem because the skin there is thin and moves constantly. The zones below are the ones that come up most often in consultation; your own map is drawn on your face, not copied from this page.

zone 01
Cheek and mid-face skin
The broadest area, and the one patients describe as dull, dry or crepey before they describe it as sagging.
zone 02
Under-eye skin
Treated with the dedicated eye line and smaller volumes. Thin skin bruises more readily here, which changes how a session is scheduled.
zone 03
Forehead and perioral lines
Fine surface lines that sit in the skin itself. Deeper expression folds belong to a different conversation.
zone 04
Neck and chest
Requested after facial treatment as often as before it. Coverage and number of points are agreed before anything is drawn up.
Signal

Mechanism

How a polynucleotide booster works once it is in the dermis

The material has no volumising job and no lifting job. It is a biological signal placed where fibroblasts live, and the pharmacology literature on polydeoxyribonucleotide — the closely related preparation that carries most of the published mechanism work — is what this class of product is argued from.

01Source

Purified DNA fragments, and no synthetic gel

The starting material is salmon-derived DNA, cut into long chains and purified so that what remains in the vial is the nucleotide chain itself. That is why the product is described in patient language as a salmon DNA injection, and why a known sensitivity to fish-derived material is worth mentioning at consultation.

02Placement

A grid of small deposits in the skin layer

Delivery is by many shallow injections across the treated zone instead of one bolus. Small raised points can be visible for a short time afterwards, which is a feature of the technique and not a sign that something has gone wrong.

03Response

The skin does the work, on its own schedule

Pharmacology reviews of polydeoxyribonucleotide describe activity at adenosine A2A receptor pathways and effects on fibroblast behaviour and tissue repair. Those papers study the material, not this clinic and not your face; they explain why the class exists, and they stop short of promising any individual outcome.

04Accumulation

The effect is cumulative, and it is reversible by time

What is injected is metabolised. Whatever improvement in skin quality follows is maintained by repeating the treatment, and it fades if you stop. Rewind's own Korean guidance for boosters gives a duration band rather than a fixed figure, because product and skin condition both move it.

Dr. Jonghwan Choi assessing the skin of the mid-face before treatment
Fig. 02 — The area is read and mapped before any injection plan is fixed
Rewind

Who plans it

Why the person holding the syringe should also be able to say no

Boosters are the easiest treatment in any clinic to sell and the easiest to over-prescribe, because they are quick and because almost nobody is refused. Rewind is a single-surgeon practice built around lifting, which changes the incentive: the same doctor who would have offered you an operation is the one deciding that an injection is enough.

01Diagnosis

Skin quality and skin descent are separated first

Dryness, fine lines and texture belong to the skin. Heaviness at the jaw or a deepened fold belongs to structure. Dr. Choi separates the two at the consultation and tells you plainly when a booster will leave the thing that bothers you exactly where it is.

02Sequence

Injectables and devices are sequenced, never stacked

Seven lifting and skin devices sit in the same clinic as the injectable menu. When more than one treatment is appropriate, the order and the spacing are decided in advance, so that aftercare instructions for one do not collide with the next appointment.

03Follow-up

The same doctor reviews what happened

Results are looked at by the person who planned them, and the plan for the next session is adjusted from what the skin actually did. International patients are supported in their own language from the first message through to that review.

Consultation room at Rewind Plastic Surgery, Apgujeong
Fig. 03 — The room where the plan is written before anything is prepared
Room

On the day

What a Rejuran appointment looks like at Rewind

Treatment room at Rewind Plastic Surgery, Apgujeong

Fig. 04 — Treatment room, where injectable sessions are carried out

Private lounge at Rewind Plastic Surgery

Fig. 05 — Private lounge on the clinic floor

You are seen by the medical director, the zone and the volume are agreed, and the injection is carried out in the clinic on the fourth and fifth floors of the Richro Building. The clinic runs by appointment only, Monday, Tuesday, Wednesday and Friday from 10:00 to 19:00 and on Saturday from 10:00 to 16:00, which is what most working patients and most visiting patients plan around.

Polynucleotide (PN) skin booster
Lines held: Healer · Eye
Multiple shallow dermal injection points
No incision and no sutures
Plan set by Dr. Jonghwan Choi
Ordinary routine resumes the same day

One thing the clinic does not publish is a fixed comfort protocol for this treatment. Rewind's Korean source pages record a numbing cream for some of its booster products and record nothing for others, so instead of guessing on your behalf, the clinic asks you to raise comfort at booking and settles it with the doctor before the first point is placed.

Record

Case photography

What Rewind can show you for skin boosters today

The clinic's photographic archive is a surgical one: standardised lighting, fixed angles, patients who consented to publication for operations. No booster series has been released for this page, so the frames stay empty and labelled instead of being filled with a stock face or a surgical case borrowed from another treatment. Ask at consultation — cases can be shown in the room under the clinic's consent rules even when they are not published on a web page.

Rejuran — case pairs

BEFORE PHOTO
AFTER PHOTO
BEFOREAFTER
case — skin booster
Rejuran
Individual results may vary.
BEFORE PHOTO
AFTER PHOTO
BEFOREAFTER
case — skin booster
Rejuran
Individual results may vary.
BEFORE PHOTO
AFTER PHOTO
BEFOREAFTER
case — skin booster
Rejuran
Individual results may vary.
BEFORE PHOTO
AFTER PHOTO
BEFOREAFTER
case — skin booster
Rejuran
Individual results may vary.

Any photograph published here will be Rewind's own patient, photographed under the same lighting and the same angle on both dates, uncropped, with written consent. Individual results may vary and cannot be promised in advance. Injection into the skin can leave bruising, small raised points, redness or swelling; a consultation with the doctor is required before any decision.

Rates

Pricing

Rejuran pricing at Rewind, Seoul

Rewind publishes one rate per vial size. What changes between two patients is how many vials the plan uses and how often it is repeated, and both of those are decided in front of you at the consultation. Package pricing across several sessions is quoted in the room after the doctor has looked at the skin.

Rejuran Healer 2ccFacial skin, single session
₩300,000
Rejuran Healer 4ccWider coverage or a combined facial and neck plan
₩600,000
Rejuran Eye 1ccUnder-eye line, lower volume
₩200,000

Rates above are list rates and VAT is added separately. Where a numbing preparation forms part of the session, its cost already sits inside the listed rate. Rewind does not run a separate foreign-patient rate, and the figure quoted in the consultation room is the figure on this list.

Fit

Suitability

Who a polynucleotide booster suits, and who is asked to wait

Usually a reasonable starting point

  • Skin that reads dry, dull or rough in photographs while the facial outline is still where you want it
  • Fine surface lines, including the ones that appear under the eye when you smile
  • Patients who want a gradual change built over several appointments instead of one visible step
  • Skin being prepared before or maintained after a device or surgical plan, in an order the doctor sets

Discussed before anything is booked

  • A heavy jaw line or a deepened fold — a booster will not move either, and the doctor will say so and explain what does
  • A known sensitivity to fish-derived material, which belongs in the conversation before the product is chosen
  • Active infection, inflamed acne or broken skin at the intended injection site
  • Pregnancy or breastfeeding, and any recent injection or energy treatment in the same area
After

Recovery

After a Rejuran session: what the clinic asks of you

Rewind's aftercare for boosters is short enough to read once and strict enough to be worth following. Mild redness or stinging can appear and settles within a few days; ordinary daily life resumes as soon as you leave.

Same day
Straight back to your day
No downtime is asked of you. Sauna, hard exercise and alcohol are left alone until the following morning.
Day 1–2
Hands off the area
The treated skin is not rubbed, massaged or pressed. Small raised points and any bruising settle over these days.
First weeks
Moisture and shade
Moisturiser and sun protection are applied carefully and without gaps while the skin responds.
Longer term
A band, and no fixed date
Rewind's booster guidance records an effect lasting from one to three months up to more than a year, depending on the product used and the condition of the skin.

Injection carries risk. Bruising, swelling, redness, stinging and small firm points at the injection sites are the common ones; infection and vascular events are rare but real, and any increasing pain, blanching or dusky discolouration is a reason to contact the clinic the same day. Tell the doctor about every treatment you have had in the same area, including fillers and energy devices.

Doctor

Professional

At Rewind, one board-certified plastic surgeon carries every case — from the first consultation to the final follow-up. Because a face is a story, and a story deserves a single author.

Dr. Jonghwan Choi, board-certified plastic surgeonRewind,
Dr. Jonghwan Choi presenting at an academic session
Fig. 06 — Academic presentation, thread-lifting session

Rewind's Doctor

Dr. Jonghwan Choi Medical Director

One surgeon, from the first
consultation to the last follow-up.

A board-certified plastic surgeon devoted to anti-aging lifting — with the precision and restraint built through years of craniofacial practice.

Board-certified plastic surgeon (Plastic Surgery)
10 peer-reviewed publications
Medical Director, Rewind Plastic Surgery
Korean Society of Plastic & Reconstructive Surgeons
Former chief director, Apgujeong Y&T Plastic Surgery
Korean Society for Aesthetic Plastic Surgery
J Craniofac Surg · JKMS · Arch Craniofac Surg
Korean Cleft Palate-Craniofacial Association
Voices

Google Reviews

What our patients say.

G 5.0 ★★★★★ 12 Google reviews · Rewind Plastic Surgery, Apgujeong — live-synced from Google Business Profile

"Sample review card — at launch this section pulls the clinic's real Google reviews automatically, shown verbatim with the reviewer's initial and posting date."

AReviewer namePOSTED ON GOOGLE

"Sample review card — reviews are never written or edited by the clinic; only what patients posted on Google appears here."

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Ask

Questions

Rejuran at Rewind — questions patients ask

What is Rejuran actually made from?
Long-chain polynucleotides purified from salmon DNA. The chains are the active material; the preparation is processed so that what is injected is the nucleotide fraction. Patients often meet the product under the phrase salmon DNA injection, which describes the origin accurately.
Is a polynucleotide booster the same thing as a filler?
No. A hyaluronic-acid filler occupies space and changes contour on the day it is placed. A polynucleotide booster is placed in the skin to prompt a repair response, and the change appears as skin quality over following weeks. See dermal filler for the contour treatment.
Which Rejuran lines does Rewind hold?
Two. The Healer line for facial skin, supplied in 2cc and 4cc, and the Eye line in 1cc for the thinner skin below the eye. Which line suits your concern is decided by the doctor after examining the area.
How many sessions will I need?
Rewind does not publish a fixed course for this treatment, and a number invented for a web page would be worth nothing to you. The doctor sets the count and the spacing at the consultation, based on the skin in front of him and on what you want from the result.
How long does the effect last?
Rewind's guidance for its booster menu gives a band of one to three months up to more than a year, moving with the product used and the condition of the skin. The material is metabolised, so the improvement is maintained by repeating and fades if treatment stops.
What will my skin look like immediately afterwards?
Small raised points at each injection site are usual and flatten over a day or two. Mild redness or a stinging feeling can follow and generally settles within a few days. Bruising is more likely in the under-eye area than on the cheek.
I am visiting Seoul for a short trip. Can I fly soon after a session?
Daily activity resumes the same day, so travel is rarely the obstacle. Bruising is the thing to plan around, particularly under the eye. Tell the clinic your travel dates when you book so the session sits early enough in your stay for a review appointment.
Does it help acne scarring and enlarged pores?
Texture work is one reason patients ask for it, and published case work on polynucleotide injection reports skin-quality outcomes. Scarring usually needs an energy treatment in the plan as well, so Rewind decides the combination and the order at consultation instead of promising one product will do it.
How is this different from a hyaluronic-acid water injection?
A water injection loads the skin with hyaluronic acid for hydration that you feel quickly and lose gradually. A polynucleotide booster leaves a signal for the skin to act on, so the timeline is slower and the target is repair instead of water content.
Can I have a device treatment in the same week?
Sometimes, and the order matters. The aftercare asks you to leave the treated skin alone for a day or two, and that is why Rewind plans the spacing between an injection and an energy session in advance instead of fitting them in as the diary allows.
What can go wrong?
Bruising, swelling, redness, stinging and small firm points at injection sites are the common events. Infection and vascular complications are uncommon but possible with any injection. Increasing pain, blanching or dusky skin means contacting the clinic the same day.
Who performs the injection at Rewind?
Dr. Jonghwan Choi, the medical director and a board-certified plastic surgeon, sees every patient and sets every plan; this is a single-surgeon practice. Interpreter-assisted consultation is available, and Rewind is a KHIDI-registered institution for international patients.
Booking

Reservation

REWIND,booking

Tell us what you are considering — we reply within one business day, in your language.

Scientific evidence

Published research on polynucleotide and PDRN preparations

The papers listed here examine polynucleotide and polydeoxyribonucleotide preparations as materials, including one study of cell proliferation outside the skin. They were not conducted at Rewind Plastic Surgery, they do not describe this clinic's patients, and no outcome reported in them should be read as a prediction for an individual.